Spontaneous Remission of Pul)monary Hypertension and Recovery from Heart
نویسندگان
چکیده
Previous reports from this laboratory have dealt with the ecologic, pathologic, clinical, and pathophysiologic features of brisket disease (1, 2). On the basis of these studies brisket disease may be defined as altitude-dependent, pulmonary, hypertensive heart disease in cattle of the species Bos taiurus. Briefly, the disease in Utah occurs primarily in young calves usually during their first exposure to conditions existing on summer ranges at elevations between 8,000 and 11,000 feet. Typical findings in animals suffering from brisket disease are outlined in Table 1. It was observed that a significant number of animals with acute brisket disease recovered when removed from the mountainous ranges and brought to Salt Lake City, Utah (elevation 4,500 feet). This observation prompted an investigation of the nature, magnitude, and time course of changes in various physiologic parameters associated with clinical recovery. The demonstration of dramatic remission from pulmonary hypertension and improvement in over-all cardiovascular function provides the basis for this report.
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